About Robert Martone & Jordan Jensen, PhD

Robert Martone is the Neuroscience Therapeutic Area Lead for the Covance Biomarker Center of Excellence. Jordan Jensen is Product Development Scientist for Antibody Products at Covance Research Products.

Examining Tau Phosphorylation as a Potential Alzheimer’s Disease Biomarker

tauWe are always on the lookout to apply the latest research to our work and contribute additional findings to the scientific community. This month we will present a poster studying the regulation of Tau phosphorylation at the upcoming 2013 Society for Neuroscience conference in San Diego.

The interest in this research was first sparked at last year’s 2012 Alzheimer’s Association International conference in Vancouver, Canada, where we heard discussions on the effects of anesthesia on Alzheimer’s disease (AD) patients. Continue reading

Biomarker Development for Parkinson’s Disease

Biomarker Development for Parkinson’s Disease

Parkinson’s Disease (PD) is a chronic neurodegenerative disease with no known cure, no certain cause, and no clinically available test for simple diagnosis. Research advances have been made, but there still remains a huge unmet need for diagnostic and disease progression biomarkers.

Research on this disease is focused on the changes that occur in the brain. Research has shown that the nerve cells in the brains of Parkinson’s patients have abnormal protein deposits that may disrupt normal brain function and cause Parkinsonian symptoms, such as tremor, slowness of movement, and rigidity, among others. Continue reading