Ulcerative Colitis Recruitment

Incorporating the patient voice to improve ulcerative colitis recruitment

The exact cause of ulcerative colitis (UC) is still unknown, but approximately 700,000 people in the United States suffer from this chronic, life-long disease that causes inflammation in the large intestine. A wide range of treatment options are available, but drug development sponsors are seeking additional ways to control inflammation, …

An introduction to dendritic cell biology and analysis using syngeneic immuno-oncology models

Productive immunotherapy driven anti-tumor responses rely on the activation of T cells that target tumor-associated antigens (TAA). The dendritic cell (DC) plays an essential role in the activation of T cell antigen-specific responses, which occur naturally in the context of infection. However, this same process supports tumor-immune surveillance as well …

Navigating COVID-19: the importance of a nimble reimbursement call center operation

COVID-19 has the potential to significantly impact call center operations. However, a proactive crisis management plan and a dispersed, redundant operating model can go a long way towards safeguarding your patient support programs. As governments and citizens address challenges posed by this global pandemic, many companies are limiting in-office operations …

science students working with chemicals in lab at the university.

Precision imaging of antibody biodistribution in vivo with Zirconium-89 PET

Zirconium-89 (89Zr) has revolutionized discovery and translation of Ab (and Ab fragment) therapeutics via PET biodistribution imaging.  With standard, straightforward labeling chemistry, 89Zr provides unprecedented specificity and sensitivity of PET Ab detection (to pM levels).  At Covance we use 89Zr PET as a platform assay for in vivo quantification of:

Addressing the challenges of data management for pharmaceutical and biotechnology companies: introducing Laboratory FSPx

Data currency management for clinical trial laboratory results can be a point of frustration for today’s pharmaceutical and biotechnology companies. Whether data is coming from a contract research organization (CRO), a central laboratory or third-party laboratories, fulfilling the need for timely availability of clean data based on unique sponsor format/industry …