Oligonucleotide therapeutics are generally single-stranded synthetic oligonucleotides with modifications in their structure to improve stability and PK properties. These therapeutics generally target RNA transcripts and reduce or modify the corresponding protein expression. Unlike most typical biologic drug classes such as monoclonal antibodies, the oligonucleotides are relatively small in size and …
Antibody Reagent Spotlight – Generating positive control antibodies for your Anti-Drug Antibody (ADA) assay
Biopharmaceuticals, including monoclonal antibodies, recombinant proteins, hormones, cytokines, growth factors, gene therapy products are a crucial class of therapeutic agents that have transformed the treatment of various diseases. As these complex molecules are introduced into patients, it is essential to monitor potential immunogenic responses. Biopharmaceuticals, including monoclonal antibodies, recombinant proteins, …
Antibody reagents for your host cell protein assay: Experience counts
In the world of biopharmaceuticals and bioprocessing, ensuring the quality, safety, and efficacy of biotherapeutic products is of paramount importance. Host cell proteins (HCPs) are a critical component to consider in this context. HCPs are proteins of the host cells, typically microbial, insect or mammalian, used in the manufacturing of …