Chemical Archives - Insights From Our Labs to Yours

Overcoming challenges in the processes of characterization, assessment, and registration of your UVCB in Europe

by Covance by Labcorpupdated on Monday, April 5, 2021Monday, March 8, 2021

The demand under European regulations for detailed environmental risk assessment of UCVBs is challenging both the industry and regulators alike. Read on to explore the challenges and possible ways of overcoming them.

What is an Inhalation reprotoxicology study – insights, advice, and secrets

by Covance by Labcorpupdated on Monday, November 16, 2020Monday, November 16, 2020

What is Inhalation Reprotoxicology and When is it Relevant? Inhalation reprotoxicology studies are required when a chemical substance or plant protection product (PPP) is suspected of having the potential to cause reproductive or developmental toxicity and there is the possibility that human exposure can occur via the respiratory system.

Five critical success factors for navigating EOGRTS complexity and smoothing the progress of your chemical registration

by Covance by Labcorpupdated on Thursday, October 29, 2020Thursday, October 29, 2020

The EOGRTS or OECD 443 is a scientifically and logistically complex study. Five critical success factors can help you overcome the complexities to achieve DART success.

How to answer basic physical chemical questions for your chemical and agrochemical substances when test guidance changes and as regulatory standards evolve

by Covance by Labcorpupdated on Monday, October 19, 2020Monday, October 19, 2020

Although most physiochemical endpoints are standard for crop and chemical active substances, selection of the right test method to assess them is critical. This blog reviews some standard endpoints and looks at the tests used, in the light of changing regulatory expectations and revised test methodologies for difficult substances.

DART: Secrets and advice on running successful studies

by Covance by Labcorpupdated on Tuesday, June 23, 2020Monday, June 22, 2020

What is DART? DART stands for ‘developmental and reproductive toxicology’ and is the acronym commonly used in place of the term reproductive toxicology. DART studies assess a chemical’s effect on several aspects of reproductive capacity in laboratory animals. These include mating performance and fertility, sexual maturation, and offspring growth and …

Chemical industry rises to COVID-19 challenge – what are the long-term implications?

by Covance by Labcorpupdated on Thursday, December 17, 2020Monday, May 4, 2020

The COVID-19 pandemic is driving a global demand for medical supplies, equipment and cleaning agents. In terms of PPE alone, the WHO estimates that there is a world-wide monthly demand for 89 million medical masks, 76 million examination gloves and 1.6 million goggles. To meet this demand, the WHO suggests …

Speeding hand disinfectant products into the EU market in response to COVID-19

by Covance by Labcorpupdated on Tuesday, June 30, 2020Wednesday, April 15, 2020

An unprecedented challenge The COVID-19 pandemic has increased the demand for hand disinfectants, driven by recommendations from bodies such as the WHO. Handwashing is a vital measure for reducing the risk of contracting the virus. The WHO specifically recommends that all individuals “regularly and thoroughly clean (their) hands with an …

K-REACH: how to register in 12 easy steps

by Covance by Labcorpupdated on Tuesday, June 30, 2020Thursday, March 26, 2020

In 2015, South Korea introduced legislation designed to protect human health and the environment from the impact of chemicals. With an estimated 44,000 chemicals in use in South Korea and about 300 new chemicals marketed annually, registrants and regulators will be kept busy assessing the risk posed to humans, animals …

How to run successful eFate studies for industrial chemicals

by Covance by Labcorpupdated on Wednesday, July 1, 2020Thursday, March 19, 2020

Environmental fate (eFate) studies are well established for crop protection chemicals and pharmaceuticals and are becoming commonplace for industrial chemicals, but what are the key considerations for setting up and running them?

New REACH nanomaterial requirements: what you need to do

by Covance by Labcorpupdated on Tuesday, June 2, 2020Monday, February 17, 2020

The new EU nanotechnology regulation On December 3, 2018, the European Commission (EC) adopted Regulation 2018/1881, amending the existing , amending the existing Registration, Evaluation, Authorization and Restriction of Chemicals (REACH) regulation, to directly address nanoparticles. The nanotechnology regulation applies to any substance that might be, or might contain, a …