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class="row"> <div id="primary" class="content-area"> <main id="main" class="site-main"> <div class="row"> <article id="post-7733" class="post-7733 post type-post status-publish format-standard has-post-thumbnail hentry category-crop category-preclinical-nonclinical category-vaccine-molecule-type tag-endocrine-disruptor latest_post" itemscope itemtype="https://schema.org/Blog"> <a href="https://blog.covance.com/2021/02/pesticide-active-ingredient-renewal-how-to-negotiate-the-eu-endocrine-disruptor-requirements/" class="post-thumbnail"><img width="450" height="300" src="https://blog.covance.com/wp-content/uploads/2021/02/Tractor-450x300.jpg" class="attachment-blossom-feminine-cat size-blossom-feminine-cat wp-post-image" alt="Tractor" data-attachment-id="7736" data-permalink="https://blog.covance.com/2021/02/pesticide-active-ingredient-renewal-how-to-negotiate-the-eu-endocrine-disruptor-requirements/tractor/" data-orig-file="https://blog.covance.com/wp-content/uploads/2021/02/Tractor.jpg" data-orig-size="642,411" data-comments-opened="0" data-image-meta="{"aperture":"0","credit":"","camera":"","caption":"","created_timestamp":"0","copyright":"","focal_length":"0","iso":"0","shutter_speed":"0","title":"","orientation":"0"}" data-image-title="" data-image-description="" data-medium-file="https://blog.covance.com/wp-content/uploads/2021/02/Tractor-300x192.jpg" data-large-file="https://blog.covance.com/wp-content/uploads/2021/02/Tractor.jpg" /></a> <div class="text-holder"> <header class="entry-header"> <div class="top"> <div class="share"> <i class="fa fa-share-alt"></i>Share <div class="social-networks"> <ul> <li><a href="https://www.linkedin.com/shareArticle?mini=true&url=https://blog.covance.com/2021/02/pesticide-active-ingredient-renewal-how-to-negotiate-the-eu-endocrine-disruptor-requirements/&title=Pesticide%20active%20ingredient%20renewal:%20how%20to%20negotiate%20the%20EU%20endocrine%20disruptor%20requirements" rel="nofollow" target="_blank"><i class="fa 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target="_blank"><i class="fa fa-envelope" aria-hidden="true"></i></a></li> </ul> </div> </div> </div><h2 class="entry-title" itemprop="headline"><a href="https://blog.covance.com/2021/02/pesticide-active-ingredient-renewal-how-to-negotiate-the-eu-endocrine-disruptor-requirements/" rel="bookmark">Pesticide active ingredient renewal: how to negotiate the EU endocrine disruptor requirements</a></h2><div class="entry-meta"><span class="byline" itemprop="author" itemscope itemtype="https://schema.org/Person"> by <span class="author vcard" itemprop="name"><a class="url fn n" href="https://blog.covance.com/author/hyacinth-chin-sue/">Hyacinth Chin Sue, Expert Consultant, CPC Crop Protection</a></span></span><span class="posted-on"><span class="text-on">updated on </span><a href="https://blog.covance.com/2021/02/pesticide-active-ingredient-renewal-how-to-negotiate-the-eu-endocrine-disruptor-requirements/" rel="bookmark"><time class="entry-date published updated" datetime="2021-02-16T14:35:03-05:00" itemprop="dateModified">Tuesday, February 16, 2021</time><time class="updated" datetime="2021-02-15T14:46:30-05:00" itemprop="datePublished">Monday, February 15, 2021</time></a></span></div><!-- .entry-meta --> </header><!-- .entry-header home--> <div class="entry-content" itemprop="text"> <p>ED assessment of active substances in PPPs came into effect in November 2018 in the EU. Insights from EFSA’s assessment of the first 65 actives shows how guidance is applied and how waivers are being used. Read on to find out how to negotiate the ED assessment process and when … </p> </div><!-- .entry-content --> <footer class="entry-footer"> </footer><!-- .entry-footer home--> </div><!-- .text-holder --> </article><!-- #post-7733 --> <article id="post-7739" class="post-7739 post type-post status-publish format-standard has-post-thumbnail hentry category-autoimmune-inflammatory category-biologics category-decentralized-clinical-trials category-drug-development category-phase-i-iia category-phase-iib-iii category-small-molecules latest_post" itemscope itemtype="https://schema.org/Blog"> <a href="https://blog.covance.com/2021/01/decentralized-clinical-trials-dct-monthly-blog-3/" class="post-thumbnail"><img width="450" height="300" src="https://blog.covance.com/wp-content/uploads/2021/02/2-12-2021-12-34-14-PM-450x300.jpg" class="attachment-blossom-feminine-cat size-blossom-feminine-cat wp-post-image" alt="2-12-2021 12-34-14 PM" srcset="https://blog.covance.com/wp-content/uploads/2021/02/2-12-2021-12-34-14-PM-450x300.jpg 450w, https://blog.covance.com/wp-content/uploads/2021/02/2-12-2021-12-34-14-PM-300x201.jpg 300w, https://blog.covance.com/wp-content/uploads/2021/02/2-12-2021-12-34-14-PM-90x60.jpg 90w" sizes="(max-width: 450px) 100vw, 450px" data-attachment-id="7740" data-permalink="https://blog.covance.com/2021/01/decentralized-clinical-trials-dct-monthly-blog-3/2-12-2021-12-34-14-pm/" data-orig-file="https://blog.covance.com/wp-content/uploads/2021/02/2-12-2021-12-34-14-PM.jpg" data-orig-size="537,360" data-comments-opened="0" data-image-meta="{"aperture":"0","credit":"","camera":"","caption":"","created_timestamp":"0","copyright":"","focal_length":"0","iso":"0","shutter_speed":"0","title":"","orientation":"0"}" data-image-title="" data-image-description="" data-medium-file="https://blog.covance.com/wp-content/uploads/2021/02/2-12-2021-12-34-14-PM-300x201.jpg" data-large-file="https://blog.covance.com/wp-content/uploads/2021/02/2-12-2021-12-34-14-PM.jpg" /></a> <div class="text-holder"> <header class="entry-header"> <div class="top"> <div class="share"> <i class="fa fa-share-alt"></i>Share <div class="social-networks"> <ul> <li><a href="https://www.linkedin.com/shareArticle?mini=true&url=https://blog.covance.com/2021/01/decentralized-clinical-trials-dct-monthly-blog-3/&title=Decentralized%20Clinical%20Trials%20(DCT)%20Monthly%20Blog%20–%20January%202021" rel="nofollow" target="_blank"><i class="fa fa-linkedin" aria-hidden="true"></i></a></li><li><a href="https://twitter.com/home?status=Decentralized%20Clinical%20Trials%20(DCT)%20Monthly%20Blog%20–%20January%202021 https://blog.covance.com/2021/01/decentralized-clinical-trials-dct-monthly-blog-3/" rel="nofollow" target="_blank"><i class="fa fa-twitter" aria-hidden="true"></i></a></li><li><a href="https://www.facebook.com/sharer/sharer.php?u=https://blog.covance.com/2021/01/decentralized-clinical-trials-dct-monthly-blog-3/" rel="nofollow" target="_blank"><i class="fa fa-facebook" aria-hidden="true"></i></a></li><li><a href="mailto:?Subject=Decentralized%20Clinical%20Trials%20(DCT)%20Monthly%20Blog%20–%20January%202021&Body=https://blog.covance.com/2021/01/decentralized-clinical-trials-dct-monthly-blog-3/" rel="nofollow" target="_blank"><i class="fa fa-envelope" aria-hidden="true"></i></a></li> </ul> </div> </div> </div><h2 class="entry-title" itemprop="headline"><a href="https://blog.covance.com/2021/01/decentralized-clinical-trials-dct-monthly-blog-3/" rel="bookmark">Decentralized Clinical Trials (DCT) Monthly Blog – January 2021</a></h2><div class="entry-meta"><span class="byline" itemprop="author" itemscope itemtype="https://schema.org/Person"> by <span class="author vcard" itemprop="name"><a class="url fn n" href="https://blog.covance.com/author/dr-bolaoyegunwa/">Dr. Bola Oyegunwa, VP & Global Head, Covance Decentralized Clinical Trials</a></span></span><span class="posted-on"><span class="text-on">updated on </span><a href="https://blog.covance.com/2021/01/decentralized-clinical-trials-dct-monthly-blog-3/" rel="bookmark"><time class="entry-date published updated" datetime="2021-03-04T17:24:18-05:00" itemprop="dateModified">Thursday, March 4, 2021</time><time class="updated" datetime="2021-01-27T13:46:00-05:00" itemprop="datePublished">Wednesday, January 27, 2021</time></a></span></div><!-- .entry-meta --> </header><!-- .entry-header home--> <div class="entry-content" itemprop="text"> <p>Welcome to the January 2021 edition of the Covance by Labcorp DCT blog. What’s Next? In the aftermath of a turbulent 2020, in which the overall industry perception of the decentralized clinical trial (DCT) approach transitioned from being “promising but still largely experimental” to “a new-normal paradigm for the industry … </p> </div><!-- .entry-content --> <footer class="entry-footer"> </footer><!-- .entry-footer home--> </div><!-- .text-holder --> </article><!-- #post-7739 --> <article id="post-7655" class="post-7655 post type-post status-publish format-standard has-post-thumbnail hentry category-biomarkers category-drug-development category-oncology category-preclinical-nonclinical latest_post" itemscope itemtype="https://schema.org/Blog"> <a href="https://blog.covance.com/2020/12/accelerating-drug-development-timelines-evolution-in-trial-design-approaches-in-oncology/" class="post-thumbnail"><img width="450" height="300" src="https://blog.covance.com/wp-content/uploads/2020/12/Wearable-Devices-450x300.jpg" class="attachment-blossom-feminine-cat size-blossom-feminine-cat wp-post-image" alt="time" srcset="https://blog.covance.com/wp-content/uploads/2020/12/Wearable-Devices-450x300.jpg 450w, https://blog.covance.com/wp-content/uploads/2020/12/Wearable-Devices-300x200.jpg 300w, https://blog.covance.com/wp-content/uploads/2020/12/Wearable-Devices-1024x682.jpg 1024w, https://blog.covance.com/wp-content/uploads/2020/12/Wearable-Devices-768x511.jpg 768w, https://blog.covance.com/wp-content/uploads/2020/12/Wearable-Devices-1536x1023.jpg 1536w, https://blog.covance.com/wp-content/uploads/2020/12/Wearable-Devices-90x60.jpg 90w, https://blog.covance.com/wp-content/uploads/2020/12/Wearable-Devices.jpg 1679w" sizes="(max-width: 450px) 100vw, 450px" data-attachment-id="7656" data-permalink="https://blog.covance.com/2020/12/accelerating-drug-development-timelines-evolution-in-trial-design-approaches-in-oncology/56240943-blue-jacket-man-use-the-smart-watch-2/" data-orig-file="https://blog.covance.com/wp-content/uploads/2020/12/Wearable-Devices.jpg" data-orig-size="1679,1118" data-comments-opened="0" data-image-meta="{"aperture":"0","credit":"","camera":"","caption":"56240943 - blue jacket man use the smart watch.","created_timestamp":"0","copyright":"sheeler\/123RF","focal_length":"0","iso":"0","shutter_speed":"0","title":"56240943 - blue jacket man use the smart watch.","orientation":"0"}" data-image-title="" data-image-description="" data-medium-file="https://blog.covance.com/wp-content/uploads/2020/12/Wearable-Devices-300x200.jpg" data-large-file="https://blog.covance.com/wp-content/uploads/2020/12/Wearable-Devices-1024x682.jpg" /></a> <div class="text-holder"> <header class="entry-header"> <div class="top"> <div class="share"> <i class="fa fa-share-alt"></i>Share <div class="social-networks"> <ul> <li><a href="https://www.linkedin.com/shareArticle?mini=true&url=https://blog.covance.com/2020/12/accelerating-drug-development-timelines-evolution-in-trial-design-approaches-in-oncology/&title=Accelerating%20drug%20development%20timelines%20–%20Evolution%20in%20trial%20design%20approaches%20in%20oncology" rel="nofollow" target="_blank"><i class="fa fa-linkedin" aria-hidden="true"></i></a></li><li><a href="https://twitter.com/home?status=Accelerating%20drug%20development%20timelines%20–%20Evolution%20in%20trial%20design%20approaches%20in%20oncology https://blog.covance.com/2020/12/accelerating-drug-development-timelines-evolution-in-trial-design-approaches-in-oncology/" rel="nofollow" target="_blank"><i class="fa fa-twitter" aria-hidden="true"></i></a></li><li><a href="https://www.facebook.com/sharer/sharer.php?u=https://blog.covance.com/2020/12/accelerating-drug-development-timelines-evolution-in-trial-design-approaches-in-oncology/" rel="nofollow" target="_blank"><i class="fa fa-facebook" aria-hidden="true"></i></a></li><li><a href="mailto:?Subject=Accelerating%20drug%20development%20timelines%20–%20Evolution%20in%20trial%20design%20approaches%20in%20oncology&Body=https://blog.covance.com/2020/12/accelerating-drug-development-timelines-evolution-in-trial-design-approaches-in-oncology/" rel="nofollow" target="_blank"><i class="fa fa-envelope" aria-hidden="true"></i></a></li> </ul> </div> </div> </div><h2 class="entry-title" itemprop="headline"><a href="https://blog.covance.com/2020/12/accelerating-drug-development-timelines-evolution-in-trial-design-approaches-in-oncology/" rel="bookmark">Accelerating drug development timelines – Evolution in trial design approaches in oncology</a></h2><div class="entry-meta"><span class="byline" itemprop="author" itemscope itemtype="https://schema.org/Person"> by <span class="author vcard" itemprop="name"><a class="url fn n" href="https://blog.covance.com/author/covance/">Covance by Labcorp</a></span></span><span class="posted-on"><span class="text-on">updated on </span><a href="https://blog.covance.com/2020/12/accelerating-drug-development-timelines-evolution-in-trial-design-approaches-in-oncology/" rel="bookmark"><time class="entry-date published updated" datetime="2020-12-22T16:09:43-05:00" itemprop="dateModified">Tuesday, December 22, 2020</time><time class="updated" datetime="2020-12-22T16:09:39-05:00" itemprop="datePublished">Tuesday, December 22, 2020</time></a></span></div><!-- .entry-meta --> </header><!-- .entry-header home--> <div class="entry-content" itemprop="text"> <p>Three specialists – Dr. Sarah Blagden, Associate Professor of Medical Oncology, University of Oxford; Maria Prendes, Head of Oncology at the Covance Biomarker Solution Center; and Kamal Saini, Senior Medical Director of Oncology at Covance – recently discussed this highly relevant topic in an educational webinar, which is now available … </p> </div><!-- .entry-content --> <footer class="entry-footer"> </footer><!-- .entry-footer home--> </div><!-- .text-holder --> </article><!-- #post-7655 --> <article id="post-7747" class="post-7747 post type-post status-publish format-standard has-post-thumbnail hentry category-autoimmune-inflammatory category-biologics category-decentralized-clinical-trials category-drug-development category-phase-i-iia category-phase-iib-iii category-small-molecules tag-decentralized-clinical-trials-dct tag-decentralized-trials latest_post" itemscope itemtype="https://schema.org/Blog"> <a href="https://blog.covance.com/2020/12/decentralized-clinical-trials-dct-monthly-blog-4/" class="post-thumbnail"><img width="450" height="300" src="https://blog.covance.com/wp-content/uploads/2021/03/DCT-450x300.jpg" class="attachment-blossom-feminine-cat size-blossom-feminine-cat wp-post-image" alt="DCT" srcset="https://blog.covance.com/wp-content/uploads/2021/03/DCT-450x300.jpg 450w, https://blog.covance.com/wp-content/uploads/2021/03/DCT-91x60.jpg 91w" sizes="(max-width: 450px) 100vw, 450px" data-attachment-id="7748" data-permalink="https://blog.covance.com/2020/12/decentralized-clinical-trials-dct-monthly-blog-4/dct-2/" data-orig-file="https://blog.covance.com/wp-content/uploads/2021/03/DCT.jpg" data-orig-size="542,356" data-comments-opened="0" data-image-meta="{"aperture":"0","credit":"","camera":"","caption":"","created_timestamp":"0","copyright":"","focal_length":"0","iso":"0","shutter_speed":"0","title":"","orientation":"0"}" data-image-title="" data-image-description="" data-medium-file="https://blog.covance.com/wp-content/uploads/2021/03/DCT-300x197.jpg" data-large-file="https://blog.covance.com/wp-content/uploads/2021/03/DCT.jpg" /></a> <div class="text-holder"> <header class="entry-header"> <div class="top"> <div class="share"> <i class="fa fa-share-alt"></i>Share <div class="social-networks"> <ul> <li><a href="https://www.linkedin.com/shareArticle?mini=true&url=https://blog.covance.com/2020/12/decentralized-clinical-trials-dct-monthly-blog-4/&title=Decentralized%20Clinical%20Trials%20(DCT)%20Monthly%20Blog%20–%20December%202020" rel="nofollow" target="_blank"><i class="fa fa-linkedin" aria-hidden="true"></i></a></li><li><a href="https://twitter.com/home?status=Decentralized%20Clinical%20Trials%20(DCT)%20Monthly%20Blog%20–%20December%202020 https://blog.covance.com/2020/12/decentralized-clinical-trials-dct-monthly-blog-4/" rel="nofollow" target="_blank"><i class="fa fa-twitter" aria-hidden="true"></i></a></li><li><a href="https://www.facebook.com/sharer/sharer.php?u=https://blog.covance.com/2020/12/decentralized-clinical-trials-dct-monthly-blog-4/" rel="nofollow" target="_blank"><i class="fa fa-facebook" aria-hidden="true"></i></a></li><li><a href="mailto:?Subject=Decentralized%20Clinical%20Trials%20(DCT)%20Monthly%20Blog%20–%20December%202020&Body=https://blog.covance.com/2020/12/decentralized-clinical-trials-dct-monthly-blog-4/" rel="nofollow" target="_blank"><i class="fa fa-envelope" aria-hidden="true"></i></a></li> </ul> </div> </div> </div><h2 class="entry-title" itemprop="headline"><a href="https://blog.covance.com/2020/12/decentralized-clinical-trials-dct-monthly-blog-4/" rel="bookmark">Decentralized Clinical Trials (DCT) Monthly Blog – December 2020</a></h2><div class="entry-meta"><span class="byline" itemprop="author" itemscope itemtype="https://schema.org/Person"> by <span class="author vcard" itemprop="name"><a class="url fn n" href="https://blog.covance.com/author/bolaoyegunwa/">Dr. Bola Oyegunwa, VP & Global Head, Covance Decentralized Clinical Trials</a></span></span><span class="posted-on"><span class="text-on">updated on </span><a href="https://blog.covance.com/2020/12/decentralized-clinical-trials-dct-monthly-blog-4/" rel="bookmark"><time class="entry-date published updated" datetime="2021-03-04T17:24:43-05:00" itemprop="dateModified">Thursday, March 4, 2021</time><time class="updated" datetime="2020-12-20T16:42:00-05:00" itemprop="datePublished">Sunday, December 20, 2020</time></a></span></div><!-- .entry-meta --> </header><!-- .entry-header home--> <div class="entry-content" itemprop="text"> <p>Welcome to the December edition of the Covance DCT blog. In our final edition for 2020, we look back on an eventful year. As we entered into the year, we had a plan for building on prior successes in patient-centric trial design. We had plans for client outreach and events … </p> </div><!-- .entry-content --> <footer class="entry-footer"> </footer><!-- .entry-footer home--> </div><!-- .text-holder --> </article><!-- #post-7747 --> <article id="post-7592" class="post-7592 post type-post status-publish format-standard has-post-thumbnail hentry category-biologics category-drug-development category-preclinical-nonclinical tag-bio-cmc latest_post" itemscope itemtype="https://schema.org/Blog"> <a href="https://blog.covance.com/2020/12/beyond-product-characterization-analytical-techniques-that-advance-biopharmaceutical-development/" class="post-thumbnail"><img width="450" height="300" src="https://blog.covance.com/wp-content/uploads/2020/11/CMC_Products-1-450x300.jpg" class="attachment-blossom-feminine-cat size-blossom-feminine-cat wp-post-image" alt="stairs leading upward" data-attachment-id="7551" data-permalink="https://blog.covance.com/2020/11/biological-characterization-of-mabs-target-binding-importance-and-characterization/stairs-leading-upward-3/" data-orig-file="https://blog.covance.com/wp-content/uploads/2020/11/CMC_Products-1.jpg" data-orig-size="1760,1067" data-comments-opened="0" data-image-meta="{"aperture":"0","credit":"","camera":"","caption":"stairs leading upward, architectural composition","created_timestamp":"0","copyright":"","focal_length":"0","iso":"0","shutter_speed":"0","title":"stairs leading upward","orientation":"1"}" data-image-title="" data-image-description="" data-medium-file="https://blog.covance.com/wp-content/uploads/2020/11/CMC_Products-1-300x182.jpg" data-large-file="https://blog.covance.com/wp-content/uploads/2020/11/CMC_Products-1-1024x621.jpg" /></a> <div class="text-holder"> <header class="entry-header"> <div class="top"> <div class="share"> <i class="fa fa-share-alt"></i>Share <div class="social-networks"> <ul> <li><a href="https://www.linkedin.com/shareArticle?mini=true&url=https://blog.covance.com/2020/12/beyond-product-characterization-analytical-techniques-that-advance-biopharmaceutical-development/&title=Beyond%20Product%20Characterization:%20Analytical%20techniques%20that%20advance%20biopharmaceutical%20development" rel="nofollow" target="_blank"><i class="fa fa-linkedin" aria-hidden="true"></i></a></li><li><a href="https://twitter.com/home?status=Beyond%20Product%20Characterization:%20Analytical%20techniques%20that%20advance%20biopharmaceutical%20development https://blog.covance.com/2020/12/beyond-product-characterization-analytical-techniques-that-advance-biopharmaceutical-development/" rel="nofollow" target="_blank"><i class="fa fa-twitter" aria-hidden="true"></i></a></li><li><a href="https://www.facebook.com/sharer/sharer.php?u=https://blog.covance.com/2020/12/beyond-product-characterization-analytical-techniques-that-advance-biopharmaceutical-development/" rel="nofollow" target="_blank"><i class="fa fa-facebook" aria-hidden="true"></i></a></li><li><a href="mailto:?Subject=Beyond%20Product%20Characterization:%20Analytical%20techniques%20that%20advance%20biopharmaceutical%20development&Body=https://blog.covance.com/2020/12/beyond-product-characterization-analytical-techniques-that-advance-biopharmaceutical-development/" rel="nofollow" target="_blank"><i class="fa fa-envelope" aria-hidden="true"></i></a></li> </ul> </div> </div> </div><h2 class="entry-title" itemprop="headline"><a href="https://blog.covance.com/2020/12/beyond-product-characterization-analytical-techniques-that-advance-biopharmaceutical-development/" rel="bookmark">Beyond Product Characterization: Analytical techniques that advance biopharmaceutical development</a></h2><div class="entry-meta"><span class="byline" itemprop="author" itemscope itemtype="https://schema.org/Person"> by <span class="author vcard" itemprop="name"><a class="url fn n" href="https://blog.covance.com/author/covance/">Covance by Labcorp</a></span></span><span class="posted-on"><span class="text-on">updated on </span><a href="https://blog.covance.com/2020/12/beyond-product-characterization-analytical-techniques-that-advance-biopharmaceutical-development/" rel="bookmark"><time class="entry-date published updated" datetime="2020-12-10T17:00:37-05:00" itemprop="dateModified">Thursday, December 10, 2020</time><time class="updated" datetime="2020-12-10T17:00:35-05:00" itemprop="datePublished">Thursday, December 10, 2020</time></a></span></div><!-- .entry-meta --> </header><!-- .entry-header home--> <div class="entry-content" itemprop="text"> <p>Evaluating your product beyond standard characterization can provide a comprehensive understanding of a molecule in early phase development. Allan Watkinson, PhD, Director of Biopharmaceutical Development CMC at Covance, recently discussed a few of the assays that can help drug development sponsors gain new insights about their product and making earlier … </p> </div><!-- .entry-content --> <footer class="entry-footer"> </footer><!-- .entry-footer home--> </div><!-- .text-holder --> </article><!-- #post-7592 --> <article id="post-7585" class="post-7585 post type-post status-publish format-standard has-post-thumbnail hentry category-biologics category-discovery category-drug-development tag-bioanalysis tag-biologics latest_post" itemscope itemtype="https://schema.org/Blog"> <a href="https://blog.covance.com/2020/12/bioanalysis-of-biologics-understanding-the-role-of-lc-ms/" class="post-thumbnail"><img width="450" height="300" src="https://blog.covance.com/wp-content/uploads/2020/12/mass-spec-2-450x300.jpg" class="attachment-blossom-feminine-cat size-blossom-feminine-cat wp-post-image" alt="mass spec 2" srcset="https://blog.covance.com/wp-content/uploads/2020/12/mass-spec-2-450x300.jpg 450w, https://blog.covance.com/wp-content/uploads/2020/12/mass-spec-2-300x200.jpg 300w, https://blog.covance.com/wp-content/uploads/2020/12/mass-spec-2-1024x683.jpg 1024w, https://blog.covance.com/wp-content/uploads/2020/12/mass-spec-2-768x512.jpg 768w, https://blog.covance.com/wp-content/uploads/2020/12/mass-spec-2-90x60.jpg 90w, https://blog.covance.com/wp-content/uploads/2020/12/mass-spec-2.jpg 1500w" sizes="(max-width: 450px) 100vw, 450px" data-attachment-id="7587" data-permalink="https://blog.covance.com/2020/12/bioanalysis-of-biologics-understanding-the-role-of-lc-ms/mass-spec-2/" data-orig-file="https://blog.covance.com/wp-content/uploads/2020/12/mass-spec-2.jpg" data-orig-size="1500,1000" data-comments-opened="0" data-image-meta="{"aperture":"0","credit":"","camera":"","caption":"","created_timestamp":"0","copyright":"","focal_length":"0","iso":"0","shutter_speed":"0","title":"","orientation":"0"}" data-image-title="" data-image-description="" data-medium-file="https://blog.covance.com/wp-content/uploads/2020/12/mass-spec-2-300x200.jpg" data-large-file="https://blog.covance.com/wp-content/uploads/2020/12/mass-spec-2-1024x683.jpg" /></a> <div class="text-holder"> <header class="entry-header"> <div class="top"> <div class="share"> <i class="fa fa-share-alt"></i>Share <div class="social-networks"> <ul> <li><a href="https://www.linkedin.com/shareArticle?mini=true&url=https://blog.covance.com/2020/12/bioanalysis-of-biologics-understanding-the-role-of-lc-ms/&title=Bioanalysis%20of%20Biologics:%20Understanding%20the%20Role%20of%20LC-MS" rel="nofollow" target="_blank"><i class="fa fa-linkedin" aria-hidden="true"></i></a></li><li><a href="https://twitter.com/home?status=Bioanalysis%20of%20Biologics:%20Understanding%20the%20Role%20of%20LC-MS https://blog.covance.com/2020/12/bioanalysis-of-biologics-understanding-the-role-of-lc-ms/" rel="nofollow" target="_blank"><i class="fa fa-twitter" aria-hidden="true"></i></a></li><li><a href="https://www.facebook.com/sharer/sharer.php?u=https://blog.covance.com/2020/12/bioanalysis-of-biologics-understanding-the-role-of-lc-ms/" rel="nofollow" target="_blank"><i class="fa fa-facebook" aria-hidden="true"></i></a></li><li><a href="mailto:?Subject=Bioanalysis%20of%20Biologics:%20Understanding%20the%20Role%20of%20LC-MS&Body=https://blog.covance.com/2020/12/bioanalysis-of-biologics-understanding-the-role-of-lc-ms/" rel="nofollow" target="_blank"><i class="fa fa-envelope" aria-hidden="true"></i></a></li> </ul> </div> </div> </div><h2 class="entry-title" itemprop="headline"><a href="https://blog.covance.com/2020/12/bioanalysis-of-biologics-understanding-the-role-of-lc-ms/" rel="bookmark">Bioanalysis of Biologics: Understanding the Role of LC-MS</a></h2><div class="entry-meta"><span class="byline" itemprop="author" itemscope itemtype="https://schema.org/Person"> by <span class="author vcard" itemprop="name"><a class="url fn n" href="https://blog.covance.com/author/covance/">Covance by Labcorp</a></span></span><span class="posted-on"><span class="text-on">updated on </span><a href="https://blog.covance.com/2020/12/bioanalysis-of-biologics-understanding-the-role-of-lc-ms/" rel="bookmark"><time class="entry-date published updated" datetime="2020-12-08T18:04:23-05:00" itemprop="dateModified">Tuesday, December 8, 2020</time><time class="updated" datetime="2020-12-09T07:00:00-05:00" itemprop="datePublished">Wednesday, December 9, 2020</time></a></span></div><!-- .entry-meta --> </header><!-- .entry-header home--> <div class="entry-content" itemprop="text"> <p>As biologics-based therapies have expanded, LC-MS is increasingly applied to support quantitative bioanalysis to detect diverse peptides and proteins. LC-MS can offer a few notable advantages compared to the traditional approach for quantification with ligand-binding assays (LBAs), but is typically thought of as a complementary approach.</p> </div><!-- .entry-content --> <footer class="entry-footer"> </footer><!-- .entry-footer home--> </div><!-- .text-holder --> </article><!-- #post-7585 --> <article id="post-7575" class="post-7575 post type-post status-publish format-standard has-post-thumbnail hentry category-biologics category-discovery category-drug-development tag-bioanalysis tag-bioanalytical-services tag-toxicology-studies latest_post" itemscope itemtype="https://schema.org/Blog"> <a href="https://blog.covance.com/2020/12/ind-enabling-programs-for-gene-and-cell-therapies-webinar-questions/" class="post-thumbnail"><img width="450" height="300" src="https://blog.covance.com/wp-content/uploads/2020/12/Webinar-2-450x300.jpg" class="attachment-blossom-feminine-cat size-blossom-feminine-cat wp-post-image" alt="Webinar" srcset="https://blog.covance.com/wp-content/uploads/2020/12/Webinar-2-450x300.jpg 450w, https://blog.covance.com/wp-content/uploads/2020/12/Webinar-2-300x200.jpg 300w, https://blog.covance.com/wp-content/uploads/2020/12/Webinar-2-1024x683.jpg 1024w, https://blog.covance.com/wp-content/uploads/2020/12/Webinar-2-768x512.jpg 768w, https://blog.covance.com/wp-content/uploads/2020/12/Webinar-2-1536x1024.jpg 1536w, https://blog.covance.com/wp-content/uploads/2020/12/Webinar-2-2048x1365.jpg 2048w, https://blog.covance.com/wp-content/uploads/2020/12/Webinar-2-90x60.jpg 90w" sizes="(max-width: 450px) 100vw, 450px" data-attachment-id="7576" data-permalink="https://blog.covance.com/2020/12/ind-enabling-programs-for-gene-and-cell-therapies-webinar-questions/39446946-professional-business-woman-at-work-with-laptop-hands-close-up/" data-orig-file="https://blog.covance.com/wp-content/uploads/2020/12/Webinar-2.jpg" data-orig-size="2508,1672" data-comments-opened="0" data-image-meta="{"aperture":"0","credit":"","camera":"","caption":"39446946 - professional business woman at work with laptop hands close up","created_timestamp":"0","copyright":"stokkete\/123RF","focal_length":"0","iso":"0","shutter_speed":"0","title":"39446946 - professional business woman at work with laptop hands close up","orientation":"0"}" data-image-title="" data-image-description="" data-medium-file="https://blog.covance.com/wp-content/uploads/2020/12/Webinar-2-300x200.jpg" data-large-file="https://blog.covance.com/wp-content/uploads/2020/12/Webinar-2-1024x683.jpg" /></a> <div class="text-holder"> <header class="entry-header"> <div class="top"> <div class="share"> <i class="fa fa-share-alt"></i>Share <div class="social-networks"> <ul> <li><a href="https://www.linkedin.com/shareArticle?mini=true&url=https://blog.covance.com/2020/12/ind-enabling-programs-for-gene-and-cell-therapies-webinar-questions/&title=IND-enabling%20Programs%20for%20Gene%20and%20Cell%20Therapies%20Webinar%20Questions" rel="nofollow" target="_blank"><i class="fa fa-linkedin" aria-hidden="true"></i></a></li><li><a href="https://twitter.com/home?status=IND-enabling%20Programs%20for%20Gene%20and%20Cell%20Therapies%20Webinar%20Questions https://blog.covance.com/2020/12/ind-enabling-programs-for-gene-and-cell-therapies-webinar-questions/" rel="nofollow" target="_blank"><i class="fa fa-twitter" aria-hidden="true"></i></a></li><li><a href="https://www.facebook.com/sharer/sharer.php?u=https://blog.covance.com/2020/12/ind-enabling-programs-for-gene-and-cell-therapies-webinar-questions/" rel="nofollow" target="_blank"><i class="fa fa-facebook" aria-hidden="true"></i></a></li><li><a href="mailto:?Subject=IND-enabling%20Programs%20for%20Gene%20and%20Cell%20Therapies%20Webinar%20Questions&Body=https://blog.covance.com/2020/12/ind-enabling-programs-for-gene-and-cell-therapies-webinar-questions/" rel="nofollow" target="_blank"><i class="fa fa-envelope" aria-hidden="true"></i></a></li> </ul> </div> </div> </div><h2 class="entry-title" itemprop="headline"><a href="https://blog.covance.com/2020/12/ind-enabling-programs-for-gene-and-cell-therapies-webinar-questions/" rel="bookmark">IND-enabling Programs for Gene and Cell Therapies Webinar Questions</a></h2><div class="entry-meta"><span class="byline" itemprop="author" itemscope itemtype="https://schema.org/Person"> by <span class="author vcard" itemprop="name"><a class="url fn n" href="https://blog.covance.com/author/covance/">Covance by Labcorp</a></span></span><span class="posted-on"><span class="text-on">updated on </span><a href="https://blog.covance.com/2020/12/ind-enabling-programs-for-gene-and-cell-therapies-webinar-questions/" rel="bookmark"><time class="entry-date published updated" datetime="2020-12-08T17:16:11-05:00" itemprop="dateModified">Tuesday, December 8, 2020</time><time class="updated" datetime="2020-12-08T17:16:07-05:00" itemprop="datePublished">Tuesday, December 8, 2020</time></a></span></div><!-- .entry-meta --> </header><!-- .entry-header home--> <div class="entry-content" itemprop="text"> <p>Get insightful answers to some common questions on IND-enabling studies for cell and gene therapies (CGTs) from a recent Covance presentation. For more information on Covance solutions, visit our Cell & Gene Therapy Education Center here.</p> </div><!-- .entry-content --> <footer class="entry-footer"> </footer><!-- .entry-footer home--> </div><!-- .text-holder --> </article><!-- #post-7575 --> <article id="post-7549" class="post-7549 post type-post status-publish format-standard has-post-thumbnail hentry category-biologics category-preclinical-nonclinical tag-cmc tag-mabs latest_post" itemscope itemtype="https://schema.org/Blog"> <a href="https://blog.covance.com/2020/11/biological-characterization-of-mabs-target-binding-importance-and-characterization/" class="post-thumbnail"><img width="450" height="300" src="https://blog.covance.com/wp-content/uploads/2020/11/CMC_Products-1-450x300.jpg" class="attachment-blossom-feminine-cat size-blossom-feminine-cat wp-post-image" alt="stairs leading upward" data-attachment-id="7551" data-permalink="https://blog.covance.com/2020/11/biological-characterization-of-mabs-target-binding-importance-and-characterization/stairs-leading-upward-3/" data-orig-file="https://blog.covance.com/wp-content/uploads/2020/11/CMC_Products-1.jpg" data-orig-size="1760,1067" data-comments-opened="0" data-image-meta="{"aperture":"0","credit":"","camera":"","caption":"stairs leading upward, architectural composition","created_timestamp":"0","copyright":"","focal_length":"0","iso":"0","shutter_speed":"0","title":"stairs leading upward","orientation":"1"}" data-image-title="" data-image-description="" data-medium-file="https://blog.covance.com/wp-content/uploads/2020/11/CMC_Products-1-300x182.jpg" data-large-file="https://blog.covance.com/wp-content/uploads/2020/11/CMC_Products-1-1024x621.jpg" /></a> <div class="text-holder"> <header class="entry-header"> <div class="top"> <div class="share"> <i class="fa fa-share-alt"></i>Share <div class="social-networks"> <ul> <li><a href="https://www.linkedin.com/shareArticle?mini=true&url=https://blog.covance.com/2020/11/biological-characterization-of-mabs-target-binding-importance-and-characterization/&title=Biological%20characterization%20of%20mAbs:%20target%20binding%20–%20importance%20and%20characterization" rel="nofollow" target="_blank"><i class="fa fa-linkedin" aria-hidden="true"></i></a></li><li><a href="https://twitter.com/home?status=Biological%20characterization%20of%20mAbs:%20target%20binding%20–%20importance%20and%20characterization https://blog.covance.com/2020/11/biological-characterization-of-mabs-target-binding-importance-and-characterization/" rel="nofollow" target="_blank"><i class="fa fa-twitter" aria-hidden="true"></i></a></li><li><a href="https://www.facebook.com/sharer/sharer.php?u=https://blog.covance.com/2020/11/biological-characterization-of-mabs-target-binding-importance-and-characterization/" rel="nofollow" target="_blank"><i class="fa fa-facebook" aria-hidden="true"></i></a></li><li><a href="mailto:?Subject=Biological%20characterization%20of%20mAbs:%20target%20binding%20–%20importance%20and%20characterization&Body=https://blog.covance.com/2020/11/biological-characterization-of-mabs-target-binding-importance-and-characterization/" rel="nofollow" target="_blank"><i class="fa fa-envelope" aria-hidden="true"></i></a></li> </ul> </div> </div> </div><h2 class="entry-title" itemprop="headline"><a href="https://blog.covance.com/2020/11/biological-characterization-of-mabs-target-binding-importance-and-characterization/" rel="bookmark">Biological characterization of mAbs: target binding – importance and characterization</a></h2><div class="entry-meta"><span class="byline" itemprop="author" itemscope itemtype="https://schema.org/Person"> by <span class="author vcard" itemprop="name"><a class="url fn n" href="https://blog.covance.com/author/covance/">Covance by Labcorp</a></span></span><span class="posted-on"><span class="text-on">updated on </span><a href="https://blog.covance.com/2020/11/biological-characterization-of-mabs-target-binding-importance-and-characterization/" rel="bookmark"><time class="entry-date published updated" datetime="2020-11-23T14:31:19-05:00" itemprop="dateModified">Monday, November 23, 2020</time><time class="updated" datetime="2020-11-23T14:31:16-05:00" itemprop="datePublished">Monday, November 23, 2020</time></a></span></div><!-- .entry-meta --> </header><!-- .entry-header home--> <div class="entry-content" itemprop="text"> <p>Demonstrating the potency of a biopharmaceutical is critical to the successful development and market release of a drug. For therapeutic antibodies, binding to the target antigen is the first step in its mechanism of action and is therefore a critical quality attribute (CQA) for the product. Since the potency assays … </p> </div><!-- .entry-content --> <footer class="entry-footer"> </footer><!-- .entry-footer home--> </div><!-- .text-holder --> </article><!-- #post-7549 --> <article id="post-7421" class="post-7421 post type-post status-publish format-standard has-post-thumbnail hentry category-biologics category-drug-development category-preclinical-nonclinical tag-antibody-dependent-cellular-cytotoxicity-adcc-2 tag-antibody-dependent-cellular-phagocytosis-adcp tag-bio-cmc tag-cmc tag-complement-dependent-cytotoxicity-assay-cdc latest_post" itemscope itemtype="https://schema.org/Blog"> <a href="https://blog.covance.com/2020/10/biological-characterization-of-mabs-role-of-fc-receptors-in-activating-and-regulating-immune-response/" class="post-thumbnail"><img width="450" height="300" src="https://blog.covance.com/wp-content/uploads/2020/10/CMC_Products-450x300.jpg" class="attachment-blossom-feminine-cat size-blossom-feminine-cat wp-post-image" alt="cmc" data-attachment-id="7420" data-permalink="https://blog.covance.com/2020/10/biological-characterization-of-mabs-assessment-of-fc-mediated-effector-function/stairs-leading-upward-2/" data-orig-file="https://blog.covance.com/wp-content/uploads/2020/10/CMC_Products.jpg" data-orig-size="1760,1067" data-comments-opened="0" data-image-meta="{"aperture":"0","credit":"","camera":"","caption":"stairs leading upward, architectural composition","created_timestamp":"0","copyright":"","focal_length":"0","iso":"0","shutter_speed":"0","title":"stairs leading upward","orientation":"1"}" data-image-title="" data-image-description="" data-medium-file="https://blog.covance.com/wp-content/uploads/2020/10/CMC_Products-300x182.jpg" data-large-file="https://blog.covance.com/wp-content/uploads/2020/10/CMC_Products-1024x621.jpg" /></a> <div class="text-holder"> <header class="entry-header"> <div class="top"> <div class="share"> <i class="fa fa-share-alt"></i>Share <div class="social-networks"> <ul> <li><a href="https://www.linkedin.com/shareArticle?mini=true&url=https://blog.covance.com/2020/10/biological-characterization-of-mabs-role-of-fc-receptors-in-activating-and-regulating-immune-response/&title=Biological%20characterization%20of%20mAbs:%20role%20of%20Fc%20receptors%20in%20activating%20and%20regulating%20immune%20response" rel="nofollow" target="_blank"><i class="fa fa-linkedin" aria-hidden="true"></i></a></li><li><a href="https://twitter.com/home?status=Biological%20characterization%20of%20mAbs:%20role%20of%20Fc%20receptors%20in%20activating%20and%20regulating%20immune%20response https://blog.covance.com/2020/10/biological-characterization-of-mabs-role-of-fc-receptors-in-activating-and-regulating-immune-response/" rel="nofollow" target="_blank"><i class="fa fa-twitter" aria-hidden="true"></i></a></li><li><a href="https://www.facebook.com/sharer/sharer.php?u=https://blog.covance.com/2020/10/biological-characterization-of-mabs-role-of-fc-receptors-in-activating-and-regulating-immune-response/" rel="nofollow" target="_blank"><i class="fa fa-facebook" aria-hidden="true"></i></a></li><li><a href="mailto:?Subject=Biological%20characterization%20of%20mAbs:%20role%20of%20Fc%20receptors%20in%20activating%20and%20regulating%20immune%20response&Body=https://blog.covance.com/2020/10/biological-characterization-of-mabs-role-of-fc-receptors-in-activating-and-regulating-immune-response/" rel="nofollow" target="_blank"><i class="fa fa-envelope" aria-hidden="true"></i></a></li> </ul> </div> </div> </div><h2 class="entry-title" itemprop="headline"><a href="https://blog.covance.com/2020/10/biological-characterization-of-mabs-role-of-fc-receptors-in-activating-and-regulating-immune-response/" rel="bookmark">Biological characterization of mAbs: role of Fc receptors in activating and regulating immune response</a></h2><div class="entry-meta"><span class="byline" itemprop="author" itemscope itemtype="https://schema.org/Person"> by <span class="author vcard" itemprop="name"><a class="url fn n" href="https://blog.covance.com/author/covance/">Covance by Labcorp</a></span></span><span class="posted-on"><span class="text-on">updated on </span><a href="https://blog.covance.com/2020/10/biological-characterization-of-mabs-role-of-fc-receptors-in-activating-and-regulating-immune-response/" rel="bookmark"><time class="entry-date published updated" datetime="2020-10-09T15:48:55-04:00" itemprop="dateModified">Friday, October 9, 2020</time><time class="updated" datetime="2020-10-19T08:00:00-04:00" itemprop="datePublished">Monday, October 19, 2020</time></a></span></div><!-- .entry-meta --> </header><!-- .entry-header home--> <div class="entry-content" itemprop="text"> <p>As well as interacting with the target antigen, antibody derived therapeutics have the potential to be able to interact with components of the immune system. Interactions with the innate immune system trigger effector functions such as antibody dependent cellular cytotoxicity (ADCC), complement dependent cytotoxicity (CDC) and antibody dependent cellular phagocytosis … </p> </div><!-- .entry-content --> <footer class="entry-footer"> </footer><!-- .entry-footer home--> </div><!-- .text-holder --> </article><!-- #post-7421 --> <article id="post-7432" class="post-7432 post type-post status-publish format-standard has-post-thumbnail hentry category-cell-gene-therapies category-drug-development category-preclinical-nonclinical category-uncategorized tag-cell-gene-therapy tag-gene-therapies latest_post" itemscope itemtype="https://schema.org/Blog"> <a href="https://blog.covance.com/2020/10/ind-enabling-programs-for-gene-therapies/" class="post-thumbnail"><img width="450" height="300" src="https://blog.covance.com/wp-content/uploads/2020/10/dna-blog-header-4-450x300.jpg" class="attachment-blossom-feminine-cat size-blossom-feminine-cat wp-post-image" alt="Gene Therapies" data-attachment-id="7435" data-permalink="https://blog.covance.com/2020/10/ind-enabling-programs-for-gene-therapies/dna-molecule-conceptual-image-2/" data-orig-file="https://blog.covance.com/wp-content/uploads/2020/10/dna-blog-header-4.jpg" data-orig-size="2448,1713" data-comments-opened="0" data-image-meta="{"aperture":"0","credit":"","camera":"","caption":"Biochemistry science concept with DNA molecule on blue background","created_timestamp":"0","copyright":"","focal_length":"0","iso":"0","shutter_speed":"0","title":"DNA molecule conceptual image","orientation":"1"}" data-image-title="" data-image-description="" data-medium-file="https://blog.covance.com/wp-content/uploads/2020/10/dna-blog-header-4-300x210.jpg" data-large-file="https://blog.covance.com/wp-content/uploads/2020/10/dna-blog-header-4-1024x717.jpg" /></a> <div class="text-holder"> <header class="entry-header"> <div class="top"> <div class="share"> <i class="fa fa-share-alt"></i>Share <div class="social-networks"> <ul> <li><a href="https://www.linkedin.com/shareArticle?mini=true&url=https://blog.covance.com/2020/10/ind-enabling-programs-for-gene-therapies/&title=IND-Enabling%20programs%20for%20gene%20therapies" rel="nofollow" target="_blank"><i class="fa fa-linkedin" aria-hidden="true"></i></a></li><li><a href="https://twitter.com/home?status=IND-Enabling%20programs%20for%20gene%20therapies https://blog.covance.com/2020/10/ind-enabling-programs-for-gene-therapies/" rel="nofollow" target="_blank"><i class="fa fa-twitter" aria-hidden="true"></i></a></li><li><a href="https://www.facebook.com/sharer/sharer.php?u=https://blog.covance.com/2020/10/ind-enabling-programs-for-gene-therapies/" rel="nofollow" target="_blank"><i class="fa fa-facebook" aria-hidden="true"></i></a></li><li><a href="mailto:?Subject=IND-Enabling%20programs%20for%20gene%20therapies&Body=https://blog.covance.com/2020/10/ind-enabling-programs-for-gene-therapies/" rel="nofollow" target="_blank"><i class="fa fa-envelope" aria-hidden="true"></i></a></li> </ul> </div> </div> </div><h2 class="entry-title" itemprop="headline"><a href="https://blog.covance.com/2020/10/ind-enabling-programs-for-gene-therapies/" rel="bookmark">IND-Enabling programs for gene therapies</a></h2><div class="entry-meta"><span class="byline" itemprop="author" itemscope itemtype="https://schema.org/Person"> by <span class="author vcard" itemprop="name"><a class="url fn n" href="https://blog.covance.com/author/covance/">Covance by Labcorp</a></span></span><span class="posted-on"><span class="text-on">updated on </span><a href="https://blog.covance.com/2020/10/ind-enabling-programs-for-gene-therapies/" rel="bookmark"><time class="entry-date published updated" datetime="2020-10-09T16:13:44-04:00" itemprop="dateModified">Friday, October 9, 2020</time><time class="updated" datetime="2020-10-09T16:13:38-04:00" itemprop="datePublished">Friday, October 9, 2020</time></a></span></div><!-- .entry-meta --> </header><!-- .entry-header home--> <div class="entry-content" itemprop="text"> <p>Gene therapies continue to hold promise as treatments for many diseases but there are numerous and unique challenges to developing them for submission as an Investigational New Drug (IND)/ Investigational Medicinal Product Dossier (IMPD) application for use in clinical trials. These applications require an optimized scientific program designed to address … </p> </div><!-- .entry-content --> <footer class="entry-footer"> </footer><!-- .entry-footer home--> </div><!-- .text-holder --> </article><!-- #post-7432 --> </div> <div class="pagination"></div> </main><!-- #main --> </div><!-- #primary --> </div><!-- .row/not-found --> </div><!-- #content --> </div><!-- .container/.main-content --> <footer id="colophon" class="site-footer" itemscope itemtype="http://schema.org/WPFooter"> <div class="site-info"> <div class="container"> <span class="copyright">Copyright © 2020 Covance Inc. 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